PCO syndrome
Polycystic ovary syndrome (PCOS) is a disease characterized by hyperandrogenemia, ovarian dysfunction and polycystic ovarian morphology. The syndrome can cause significant metabolic disorders, thereby increasing the risk of diabetes mellitus and cardiovascular disease.
Insulin resistance is present in many women with PCOS, particularly those with hyperandrogenemia.
Aetiology
The contribution of the genetic background remains uncertain. There is no genetic test to use as a means of population control. There is no environmental agent or substance involved in the onset of the syndrome. Insulin resistance plays a central role in the etiology of insulin. Obesity is not a diagnostic criterion (given that 20% of women with PCOS are not obese). It strengthens though the pathological phenomena of the syndrome.
Symptoms
Women with PCOS usually have menstrual disorders (from amenorrhea to menorrhagia) and infertility. For this reason, the focus is on ovulation induction therapies. They increase the risk of ovarian hyperstimulation syndrome and multiple pregnancies.
Furthermore, women with PCOS have an increased risk of pregnancy complications. For example diabetes mellitus and hypertension. Dermatological disorders due to increased peripheral androgens, such as hirsutism and acne and, to a lesser extent, alopecia, are common results.
Scientists report that these women have an increased risk of endometrial cancer through the independent risk factors that accompany the syndrome (obesity, diabetes, hypertension, chronic anovulatory cycles).
Differential diagnosis
Diagnosis
The history should focus on the onset and duration of various signs of hyperandrogenemia, the history of menstruation and the simultaneous intake of drugs, especially exogenous androgens.
> 12 follicles of 2-9mm
PCOS and diabetes type 2
Studies have shown that women with PCOS have a 2 to 5 times greater risk of developing type 2 diabetes. Therefore, the doctor must control it by doing a load curve.