Kardalas Efstratios 1 , Sakkas Evangelos 1 2 , Ruchala Marek 3 , Macut Djuro 4 , Mastorakos George 5

Affiliations expand

PMID: 34529221 DOI: 10.1007/s11154-021-09685-7


The complex mechanisms, which are related to the pathophysiology and the development of autoimmune thyroid diseases, involve transforming growth factor beta (TGF-β) and its interplay with the immune system. The aim of this review is to examine the role of TGF-β regarding thyroid autoimmunity and explore the potent role of this molecule either as a diagnostic or prognostic marker or a therapeutic target regarding autoimmune thyroid diseases. TGF-β is clearly a master regulator of the immune response, exerting either inhibitory or facilitatory effects on cells of the immune system.

ORIGINAL RESEARCH article – Front. Neurosci., 04 August 2021 |

Panagiota Konstantakou1,2, Nikos Chalarakis3, Georgios Valsamakis1, Evangelos Grigoriou Sakkas1,4, Eleni Vousoura3, Alexandros Gryparis1, Grigorios Evangelou Sakkas4, George Papadimitriou3†, Ioannis Zervas3† and George Mastorakos1*†
1Unit of Endocrinology, Diabetes Mellitus and Metabolism, Medical School, Aretaieion Hospital, National and Kapodistrian University of Athens, Athens, Greece
2Unit of Endocrinology, Diabetes Mellitus and Metabolism, Alexandra General Hospital, Athens, Greece
3Department of Psychiatry, Eginition Hospital, Athens University Medical School, Athens, Greece
4Rea Maternity, Private Hospital, Athens, Greece

Publication. Authors: Evangelos G. Sakkas, Raffaella Votino, Maria Papagianni, George Mastorakos. Anastasios Chatziaggelou

A very interesting speech took place on 25/10/2017 (at 19:00) at the theatre “Karolos Koun”. Its title was “Myths and Truths in In Vitro Fertilization”. It was an initiative of the Volunteer Group of the Municipality of Alimos and its Youth Center. The Obstetrician Gynecologist, Dr. Evangelos Sakkas was the main speaker, who specializes in in vitro fertilization and gynecological endocrinology.

Πραγματοποιήθηκε με μεγάλη επιτυχία το 2ο συνέδριο λαπαροσκοπικής ογκολογικής χειρουργικής στην Γυναικολογία στο νοσοκομείο ΡΕΑ. Η Dr. Votino Raffaella συμμετείχε και προέδρευσε την πρώτη μέρα σε ένα Session με εξαιρετικούς ομιλητές.

The role of cortisol and TGFB on thyroid function during pregnacy and postrartum period.