In Vitro Fertilization (IVF)

IVF Gyn Care
Εξωσωματική γονιμοποίηση (IVF)
Gyn Care IVF

In Vitro Fertilization (IVF)

In vitro Fertilization (IVF) is part of the assisted reproductive methods. It has been carried out for 40 years all over the world. The first child, born with this method was Louise Brown. She was born in 1978. In Greece, the first IVF procedure took place on 20 January 1982. Stella Iordanidou, who was entitled to the first IVF procedure, Gave birth to Christina Iordanidou with c-section. This birth was the 13th with the IVF procedure worldwide.

What it is

Thanks to this method millions of couples fill their arms and their hearts up every day.

ivf procedure
What does IVF mean?

We call this procedure IVF (In Vitro Fertilization) because it is based on the fertilization of the woman’s eggs by the man’s spermatozoon in the laboratory and not in the woman’s body.

Why do I need IVF?

When does a couple ends up choosing this method? How does the doctor decide to suggest this procedure? A lot of women wonder: “when do I follow an IVF procedure?”

The In Vitro Fertilization is not the first option of any couple. In addition, it is not the first option of the specialists either.

If a woman hasn’t conceived after a year of intercourse without protections, we start investigating infertility matters. After a woman turns 35 years old, this time period decreases to 6 months. This happens because a woman’s fertility is diminished year by year. According to the European Society of Human Reproduction and Embryology (ESHRE) 1 out of 6 couples worldwide face infertility matters.

Our gynecologist specialized in IVF, after having analyzed the specialized examinations, analyzes the reasons of the couple’s infertility. He also analyses the causes and the medical profile of both the man and the woman, so he can come to a conclusion. After that, he proposes the best choice of assisted reproductive method.

Poor egg quality.
Primary Ovarian Insufficiency.
Hormonal problems. Premature menopause.
Endocrine problems.
Anatomy problems.
Fallopian tube problems.
History of repeated failed attempts with her own eggs.
Recurrent miscarriage. Connect to our facebook page to watch everything the doctor describes in detail.

Chronic infections
Ostruction or absence of sperm in the semen
Ejaculatory dysfunction
Genetic causes
Sperm problems

Cancer for which they received chemotherapy and/or radiation therapy in the pelvis area.
Serious hereditary diseases.

About the exams that men and women must do, read more in the section Infertility.

 We wrote a useful article for you that you have to read. Its title is In Vitro Fertilization causes and stages.

What does the couple need to know when starting an IVF attempt?

The drugs that doctors give to the woman are injected subcutaneously and easy to use. The woman can do it by herself. She doesn’t have to change anything on her daily routine.

The cure doesn’t affect at all the couple’s life. Apart from the ultrasounds and the medicine the couple can do everything they did. The woman can exercise, have fun and intercourse with her partner. At the last stage of the procedure, the embryo transfer, the doctor gives specific instructions to the couple. There aren’t any significant restrictions though.

couple tries for successful pregnancy
The IVF procedure

The IVF procedure isn’t painful at any stage. It lasts 10 days or 20-30 days, depending on the chosen protocol.

The IVF steps are simpler than you imagine:

  • Ovarian stimulation provocation and monitoring.
    First, we inject hormones to stimulate the ovaries for a few days. At this point we monitor the ovulation by doing 2 or 3 vaginal ultrasounds

  • Egg retrieval
    After that we retrieve the eggs. This procedure is performed under sedation and is painless. The woman may need to take the day off due to sedation. The follicular fluid suction takes from 10 to 20 or even 30 minutes, depending on the number of follicles present.

  • Sperm Collection
    The man’s sperm is collected on the same day.

  • Fertilization

    (conventional procedure or IntraCytoplasmic Sperm Injection (ICSI)). Blastocyst culture. Fertilization check and embryo growth.
    The embryologist undertakes the egg fertilization. Depending on the circumstances, he either chooses the conventional IVF method or the ICSI.
    Conventional IVF if:

    • the sperm is perfect
    • It’s the woman’s first attempt
    • there is a high number of eggs

    In this case, the embryologist puts together the eggs and the sperm overnight. The next day he checks which eggs have been fertilized.

    IntraCytoplasmic Sperm Injection (ICSI)

    The embryologist chooses the ICSI method when we have:

    • Sperm of poor quality
    • Low eggs number
    • More than one IVF attempts
    • Low fertilization rate
  • Embryo transfer
    The final stage is performed 3 to 5 days after oocyte retrieval. The procedure is performed using a special flexible thin catheter, in which the embryos are loaded. This stage is totally painless for the woman. It needs no sedation or special preparations.

In our team we always use the  ICSI  where the embryologist amplifies the spermatozoa under a special microscope. This helps him choose the most suitable sperm.

It’s a critical moment, but with the experience of the embryologist, along with a fully equipped laboratory can contribute to a successful pregnancy.

Innovative Methods
Methods and Techniques: IVF

We can do the In Vitro Fertilization in these ways:

Fertilizatiοn in natural cycle: It takes place in the embryology laboratory. During a natural cycle IVF there is no ovarian stimulation with drugs. We use the single (predominant) follicle and of the endometrium. However, the disadvantage of this way is the low success rates compared to the conventional IVF method.

The conventional IVF method begins with ovarian stimulation with drugs in order to develop multiple mature follicles simultaneously.

IntraCytoplasmic Sperm Injection (ICSI): This method is used when sperm penetration to the egg is blocked due to male infertility. In this procedure the most mature eggs are chosen and carefully cleansed. The fertilization takes place 2-10 hours after egg retrieval. A hole is opened in the egg cover, so that the spermatozoon can enter the egg.

On what does the success of the IVF depend?

The reasons of a failure can be various and complicated. The age defines the outcome of the process, as it affects the quality of the eggs and the sperm.

Watch the video where Dr Evaggelos Sakkas explains the implantation failure.

This fact doesn’t exclude older women to experience the miracle of motherhood. The success of the In Vitro Fertilization depends mostly on the quality of the egg and the embryo.  For this reason there are women who conceive on the first attempt, whereas there are other women who need to try more.

It is very important the fact that Athens is considered a reference point in assisted reproductive procedures. This happens because the cost in Greece is lower compared to the USA, but with the same success rates.

IVF: What happens if it fails?

The failure generates feelings of frustration and “mourning”. It is totally normal not just for the couple, but for the whole scientific team who feels your pain.

Our experience though makes us confident to reassure you that the one who insists, wins. Every couple that wants to fill their arms, will make it happen. It doesn’t happen the same way for all families… but the result is the same in any case.

  • Hope is not lost in science.
  • Regain you resilience and we will be by your side to support you by all means. Our psychologist Rozina Palaiologou can help you deal with every difficulty you face. Read her very helpful articles on our blog.
Failure IVF
What are the steps after a failure?

First of all, we give yourself some time to deal your previous attempt. Most of the times IFV fails for reasons that the couple cannot control.

According to the British Human Fertilisation & Embryology Authority (HFEA), the IVF procedure is besides healing, a diagnostic method. So, depending on the stage of the process in which there was difficulty, we modify the strategy of the next attempt, request further examinations or invasive approaches.

IVF success rates

In our country, the success rates are usually between 25%- 45%. In more detail, with honesty and scientific evidence we have written the article “IVF and insemination” for you.

IVF Cost

How much does the IVF procedure cost?

The creation of a new life cannot be counted in numbers or money. Its value is priceless. However, the economic reality at the time has created obstacles and additional difficulties. The In Vitro Fertilisation is an expensive process. We may choose the techniques and the approaches during the process, so it is quite difficult to determine the cost from the beginning.

The Greek National health insurance system EOPPY engages to a considerable extent. About the drugs and the committee of EOPYY you can be informed here.

The GynCare team supportrs the couples who want to become parents by offering competitive financial service packages.
The reason we keep our therapy cost in low levels is mainly because:
  • We only charge you for the services you really need and not for standard financial packages.
  • We simplify the procedure through innovative methods
  • High success rates on the first attempt.

Our values and vision lead us to offer the best at affordable prices.
We let nothing stand in your way…

IVF: when and how often do we try?

The time period of the next attempt depends on:

  1. The couple’s psychological situation
  2. The ovarian stimulation with drugs. We suggest 3-4 months between the attempts
  3. The protocol
  4. The existing frozen embryos

Our principle is 4 cycles per year.

Finally, the EOPYY committee defines the 4 months between attempts. It also covers 4 attempts in total.


In Vitro Fertilisation:

Myths and Truths

Finally, try to get information only by trusted sources because we can find many false information. We suggest you reading the article “In Vitro Fertilisation Myths and Truth” which is based on scientific facts.

Gyn Care Ivf

Which is the best IVF center in Athens?… Lots of anxious couples wonder.

The place where you will undergo the IVF procedure is a very important decision, in order to avoid the suffering and wasting money. What you have to know is that the success of any attempt depends, not only on proper medical care, but also on the combination of the specialized doctors and the scientific staff that you trust.

The GynCare fertility specialists commit to you the above. They:

  1. believe in Humanitarian values
  2. make decision according to medical ethics
  3. all members of our team do their best
  4. are trained in innovative techniques
  5. speak the language of scientific truth
  6. emphasize on your wide-range information, so you know all the choices at your disposal.

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