Until recently, patients with premature menopause or low ovarian reserve were destined to egg donation.
The injection of PRP into their ovaries has come to give hope and change the landscape of IVF.
We recall that the classic PRP method uses the patient’s own blood. First, the doctors centrifuge it and they isolate the growth factors. Then, this cocktail of growth factors, through the needle used in oocyte pick-up, is injected into the ovaries. This procedure leads to a short-period but adequate revascularization of the ovarian tissue. This method had and has relatively good results.
However, it does not seem to have the same results in all patients. It is probable that due to the method of intravaginal infusion under ultrasound monitoring, PRP does not manage to reach the ovarian stroma. It is also possible that part of it finishes in the abdomen. This happens in cases where the ovaries are atrophic (common in premature menopause) and therefore very small. Or when the ovaries are out of position as is the case with patients with a history of endometriosis.
In these cases we now propose the laparoscopic PRP. It is the surest method of ovarian regeneration with the best results.
The pioneering idea behind the laparoscopic method is that the ovary is initially prepared and exposed with appropriate incisions that allow PRP to reach precisely and targeted the ovarian circulation. The incisions cause a local activation of the growth factors that prepare the soil for the PRP receptor.
With this method the patient undergoes laparoscopy and general anesthesia. Our experience in the field is enormous and it is a day surgery intervention, with means that the patient can return home the same night.
We have been using this method for 6 months with particularly good results, achieving so far 5 pregnancies.