{"id":4083,"date":"2019-02-07T08:51:40","date_gmt":"2019-02-07T08:51:40","guid":{"rendered":"http:\/\/localhost\/testsakas\/first-series-of-18-pregnancies-after-ulipristal-acetate-treatment-for-uterine-fibroids\/"},"modified":"2021-08-02T11:31:14","modified_gmt":"2021-08-02T11:31:14","slug":"first-series-of-18-pregnancies-after-ulipristal-acetate-treatment-for-uterine-fibroids","status":"publish","type":"page","link":"https:\/\/www.gyn-care.gr\/it\/first-series-of-18-pregnancies-after-ulipristal-acetate-treatment-for-uterine-fibroids\/","title":{"rendered":"First series of 18 pregnancies after ulipristal acetate treatment for uterine fibroids."},"content":{"rendered":"

First series of 18 pregnancies after ulipristal acetate treatment for uterine fibroids.<\/h1>\n<\/div>
<\/div><\/div><\/div>

Luyckx M, Squifflet JL, Jadoul P, Votino R, Dolmans MM, Donnez J.<\/p>\n<\/div>

Abstract<\/h4>\n<\/div>

OBJECTIVE:<\/h4>\n<\/div>

To study the pregnancy rate after ulipristal acetate (UPA) therapy for fibroids.<\/p>\n<\/div>

DESIGN:<\/h4>\n<\/div>

Retrospective analysis of a series of 52 patients prospectively included in the PGL4001 (ulipristal acetate) Efficacy Assessment in Reduction of Symptoms Due to Uterine Leiomyomata (PEARL) II and III trials.<\/p>\n<\/div>

SETTING:<\/h4>\n<\/div>

Academic hospital.<\/p>\n<\/div>

PATIENT(S):<\/h4>\n<\/div>

Among the 52 patients, 21 wished to conceive upon treatment completion.<\/p>\n<\/div>

INTERVENTION(S):<\/h4>\n<\/div>

None.<\/p>\n<\/div>

MAIN OUTCOME MEASURE(S):<\/h4>\n<\/div>

Pregnancy rate and live birth rate.<\/p>\n<\/div>

RESULT(S):<\/h4>\n<\/div>

Twenty-one patients attempted to get pregnant, among whom 15 (71%) succeeded, totaling 18 pregnancies. Among these 18 pregnancies, 12 resulted in the birth of 13 healthy babies and 6 ended in early miscarriage. No regrowth of fibroids was observed during pregnancy.<\/p>\n<\/div>

CONCLUSION(S):<\/h4>\n<\/div>

We report the first series of pregnancies achieved after UPA treatment. Our data confirm a sustained long-term effect after UPA therapy.<\/p>\n<\/div>

Copyright \u00a9 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.<\/p>\n<\/div>

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