Thyroid autoimmunity, hypothyroidism and ovarian reserve: a cross-sectional study of 5000 women based on age-specific AMH values.
Nikolaos P. Polyzos, Evangelos Sakkas, Alberto Vaiarelli, Kris Poppe, Michel Camus, and Herman Tournaye
Study question:
Is there any association between thyroid autoimmunity (TAI) and diminished ovarian reserve (DOR)?
Summary answer:
TAI and hypothyroidism have nothing to do with low ovarian reserve.
What is known already:
First of all, TAI is a common co-existent endocrinopathy in women with primary ovarian insufficiency. Also, several studies support a potential link between TAI and the reduction in ovarian reserve. However, robust evidence regarding its prevalence in women with DOR is lacking.